JMOfartO:
I would echo what Dibs50 said in his first statement..
RELIABILITY....
I know the age old argument of "expansion" vs "penetration" and I'm of the opinion that IF you have a particular round that works for you it really doesn't matter much if that round is a jhp or fmj in a close up personal encounter such as we all fear..
My thinking (probably incorrect, but I'm old and opinionated and facts sway me very little) is that FOR MY NEEDS any self defense shooting will be very close up and IF the cavity in the nose of my jhp round of choice (Speer Gold Dot jhp's feed like corn thru a goose in my LWS380) gets clogged up with debris from any outer garment it will then just magically transform into a fmj round and go on about it's business.
Or, my first, second and probably 3rd priority in my self defense weapon is RELIABILITY, and everything else is of lesser concern.
In the first place most "knowledgeable" gun "experts" will tell you that a 380 round is basically worthless for self defense anyway, and anything less than a 45ACP round is just designed to upset (can't say "piss off" ) the shootee..
And to those esteemed experts I say I've yet to find a way to successfully, comfortably, and realistically conceal carry a 45ACP on my small frame. Add the heat and humidity factor here in S.E. Ga. and it's simply not a choice, for me.
Hey, I have one, a very nice (imo) CS45 and if I plan to drive thru any neighborhoods or areas who's streets are named for a deceased Baptist preacher I try and bring it along.. But without an outer garment (shirt/coat/etc.) it STILL cannot be carried concealed.
I CAN take my Seecamp LWS380 anyplace, anytime, with none the wiser, and in complete comfort.
I'm not a brain surgeon and do not profess to have any skills in rocket science, but I DO believe that 7 380cal. Gold Dot jhp's available in my pocket are worth much more than the 7 flying ashtray rounds in my CS45 back at home..
I would suggest you find a good self defense round that works reliably in your weapon of choice and go about your business. JHP/FMJ? Just a toss-up as far as I'm concerned. I cannot use fmj's in my Seecamp anyway, but if I had the choice I think I'd still stick to jhp's.
I'm a big believer that having a reliable pistol of ANY caliber on you when needed is light years better than not..
With my small caliber self defense weapons I practice from 3 yards, max... If you shoot someone from further out you open yourself up for criticism from those who would say you should have retreated rather than firing..
Most of regular folks (non leo's) will never have to shoot someone in defense of our lives. IF and when we do tho, it will probably happen very quickly, from very close up and if you are very, very lucky you might have time to just pull your weapon out, point it in the general direction of the threat and pull the trigger..
It'll be strictly "point and shoot" and if you have lots of practice from close up and personal range it just offer you the skill of actually hitting what you are being threatened by.
Generally in such a situation regular folks need a little luck, and an absence of "Murphy's Lsws" to come out a winner.
But simply HAVING a weapon available puts you heads and heels ahead of those folks who love a "cocked and locked" 45ACP choice, but had to leave it at home, or in the car.
Just personal opinion, no offense intended to anyone, and sorry to ramble, but it's what I do.

Best Wishes,
Jesse